Discovery of JAK2/3 Inhibitors from Quinoxalinone-Containing Compounds
Kamonpan Sanachai, Panupong Mahalapbutr, Lueacha Tabtimmai, Supaphorn Seetaha,Tanakorn Kittikool, Sirilata Yotphan, Kiattawee Choowongkomon,* and Thanyada Rungrotmongkol* Janus kinases (JAKs) are involved in a wide variety of cell signaling associated with T-cell and B-cell mediated diseases. The pathogenesis of common lymphoid-derived diseases and leukemia cancer has been implicated in JAK2 and JAK3. Therefore, to decrease the … Continue reading Discovery of JAK2/3 Inhibitors from Quinoxalinone-Containing Compounds
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